Each WordPress installation needs its own Premium license. If you have created a network of sites using WordPress multisite (http://codex.ww.wp.xz.cn/Create_A_Network) then only one Premium license is needed to cover all the sites. If you have setup a main site and secondary site under the same WordPress installation, then only one Premium license is needed.
For example:
Subdomains such as site1.mysite.com and site2.mysite.com each need their own Premium license unless setup as a multisite network.
Subdirectories such as mysite.com/site1 and mysite.com/site2 each need their own Premium license unless setup as a multisite network.
Main domain and subdomain such as mysite.com and mysite.com/blog setup under one WordPress installation, only one Premium license is needed.
Many thanks. My site is set up as a multisite network. There is a single word press installation.
If it is just one wordpress installation, you only need one premium key.
Per forum rules, we aren’t allowed to really answer questions about premium features or licenses. You can email us at presales [at] wordfence [dot] com. Keep in mind that address is not for support questions.
tim