alignment help

im running 2.6.1 not that that helps i made a layout and i see it fine on my browswer with a 1024×768 view, but when my friends with a 1280×1024 view see it its all messed up. i know it has to do with my css and margins im not to good at coding wordpress. here are pics to see what im talking about
what i see
what other people see