Browsing Entries without Refreshing

Just wondering if it’s possible to scroll wordpress entries without refreshing the entire page, just the one part of the page that has the post.

Hard to explain but if you check this out (work warning, has the occasional girls in lingerie on the front page)

http://www.forgetfoo.com/

and if you click on the links on the right the content automatically loads up. I think this is a really cool idea, just wondering if there was a way I could do something similar with wordpress. (ps. his site is done with coldfusion and lot’s of javascript)