front-page.php

Hello, I have done hella research on trying to figure this out. Searching forums, blogs, wordpress codex.

Please can somebody shoot me in the direction of getting a front-page set up. Truthfully I would like to set a new stylesheet for just my landing page. But if there is another way, i am open to whatever. I am running Genesis Framework, trying to build my theme from a sample blank theme. How can I get a whole set of new css rules for a single page opposed to the whole site? With out a Plug-in. ?

Can Anyone hear me????