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  • I’d recommend you start with APC (APCU in php 5.4+ if you use Opcache as well).

    Switch to Memcache when you will need to deploy the site on multiple servers; that would be a scenario of hundreds of pageviews at the same time.

    APC(U) would be even faster on a single server as you access everything internal PHP – APC, as on PHP – Memcache you have a special network layer, and you have also the network delay as well (if you have separate servers).

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