Solved! It works with the permission 777. Thanks again Greg.
Wow thats fast! Many thanks Greg.
The first error we have solved.
I have created the folder wp-statics in uploads with the pemissions 755.
The geoip.dat is also in uploads with permission 644.
Tom
Warning: fopen(/www/htdocs/wxxxx/www.xxxxx.de/wp-content/uploads/wp-statistics/GeoLite2-Country.mmdb): failed to open stream: Permission denied in /www/htdocs/wxxxxx/www.xxxxx.de/wp-content/plugins/wp-statistics/wps-updates.php on line 41