This has suddenly begun happening to all comemnts on my blog as well.
All comments, from various users (many of whom are regular commenters) are going straight into spam. Even reply comments that I make while logged in as admin are going into spam.
I have approved all non-spam comments that are in the spam folder, but Akismet does not seem to be recognizing that (e.g. even after several days, my reply comments are still being flagged as spam).
I haven’t made any changes/upgrades to my site; it appears this issue began spontaneously about a week ago.