Apparently the only thing that esmi knows about this topic is gender differentiation and probably should’ve left this one alone. That is not what you call support.
What she was trying to tell you is that you can override any of these settings by defining its respective constant (rather than editing the database) in wp-config.php.
Make a section for yourself, with a comment line, for overrides, then paste the following on its own line:
define(‘UPLOADS’, ‘wp-content/uploads’);
Inside the second argument, you should put the relative path to your uploads directory (either way, it defaults to wp-content/uploads). Keep in mind, this will not bring the option under settings back, but you can just use config.php in the future.